Intraconazole 4% / Phenytoin Sodium 3% / Stera Base Available in 120 g, 240 g
(In-Office Compounding Kit)
Active-Prep Kit V 60g NDC #: 45861-0116-03 Active-Prep Kit V 120g NDC #: 45861-0116-02 Active-Prep Kit V 240g NDC #: 45861-0116-01
ACTIVE Prep Kit V contains Itraconazole 4%, Phenytoin Sodium 3% and Stera Base, a delivery vehicle proven to offer superior carrying capacity of active ingredients. Using this kit, clinicians can compound topical treatments that support and manipulate multiple aspects of the wound healing process as needed for each patient. Combining various medications into one topical cream also improves adherence and may reduce wound care costs.
Pharmaceutica North America guarantees that all of the ingredients in ACTIVE Prep Kit V are manufactured and distributed in accordance with cGMP at an FDA and DEA registered facility. Offering customized wound care is cost-effective and easy to prepare using the pre-measured and sterile ingredients contained in the compounding kit.
Approved and Potential Uses of Topical Itraconazole and Phenytoin:
Itraconazole is a triazole antifungal agent that selectively inhibits cytochrome P-450-dependent enzymes. Without these enzymes, ergosterol synthesis is impaired, which inhibits fungal cell wall synthesis. It may also inhibit endogenous respiration, impair triglyceride and/or phospholipid biosynthesis, and interact with membrane phospholipids. Itraconazole is used against histoplasmosis, blastomycosis, cryptococcal meningitis, aspergillosis, onychomycosis and diverse dermatomycoses.
Phenytoin Sodium is known as an anticonvulsant and muscle relaxant, but as a topical agent it’s used to promote wound healing. It likely works through several mechanisms of action that modulate various stages of wound healing. It’s known to promote granulation, but may also stimulate fibroblast proliferation, inhibit collagenase activity and promote collagen formation.
Stera Base is an emollient oil-in-water emulsion that’s stable over a wide pH range, compatible with diverse active pharmaceutical ingredients, and proven to be an excellent base that promotes penetration and retention of active ingredient.
Consider using ACTIVE Prep Kit V to promote wound healing associated with the following conditions:
Diabetic foot ulcers
Venous stasis ulcers
Leprosy trophic ulcer
When you purchase ACTIVE Prep Kit V from Pharmaceutica North America, you’re guaranteed competitive pricing provided by one of the nation’s leading compounding pharmaceutical companies. Our team of experts is dedicated to solving your pharmaceutical problems and navigating the supply chain to ensure you always have the products you need. Contact us today to learn about our fast shipping and how we can work together to provide high-quality pharmaceutical products for your clients.