Diclofenac Sodium 1.5%

Topical Solution 1.5% – 150 ml (24 units)
NDC#: 45861-0062-05


Diclofenac Sodium 1.5% in the form of a topical Solution relieves pain and inflammation arising from degenerative joint disease. Its efficacy is superior to placebo and similar to oral Diclofenac when used to treat osteoarthritis, which is the most common type of joint disease and the leading cause of chronic disability in elderly Americans. Patients who use topical Diclofenac Sodium 1.5% may have better tolerance for two key aspects of nonpharmacologic therapy—physical therapy and exercise.

Pharmaceutica North America is proud to be a reliable supplier of high-quality Diclofenac Sodium 1.5% and one of the nation’s leading compounding pharmaceutical companies. Our team is dedicated to providing first-class customer service, through individual attention together with collaborative teams to deliver prescriptions product in the form and dose that’s optimal for our customers.

Approved and Potential Uses of Diclofenac Sodium 1.5% Solution:  

As an NSAID that’s partially selective for COX-2 but inhibits both COX-1 and COX-2, Diclofenac Sodium 1.5% decreases the formation of proinflammatory prostaglandins. It may further exert an anti-inflammatory effect by inhibiting chemotaxis and neutrophil aggregation or lowering levels of cytokines. Consider using it for the following conditions:

  • Osteoarthritis of the knee – Diclofenac Sodium 1.5% Solution has been approved for relieving osteoarthritis-associated pain and inflammation in the knees. However, Phase III clinical trials found that it was well tolerated and effective when used to treat hand and knee osteoarthritis in patients aged 75 years or older. 1
  • Rheumatoid arthritis – Topical Diclofenac Sodium 1.5% provides some relief for pain caused by rheumatoid arthritis, but it’s typically used in combination with systemic agents.
  • Neuropathic pain – A small, randomized, placebo-controlled, double-blinded, crossover clinical trial explored the efficacy of topical Diclofenac 1.5% on patients with postherpetic neuralgia and complex regional pain syndrome. Based on a visual pain scale—and corroborated by quantitative sensory testing—subjects using topical Diclofenac had lower overall pain scores. 2  

When you purchase Diclofenac Sodium 1.5% Solution from Pharmaceutica North America, you’re guaranteed competitive pricing and a stable product that was manufactured and distributed in accordance with cGMP at an FDA and DEA registered facility. Contact us today to learn about our fast shipping and how we can work together to provide high-quality pharmaceutical products for your clients.

Diclofenac Sodium 1.5% Fact Sheet


Show 2 footnotes

  1. “Pooled Safety Analysis of Diclofenac Sodium Topical Solution 1.5% (w/w) in the Treatment of Osteoarthritis in Patients Aged 75 Years or Older,” June 2012, https://www.ncbi.nlm.nih.gov/pubmed/22791985
  2. “Effect of 1.5% Topical Diclofenac on Clinical Neuropathic Pain,” July 2015, https://www.ncbi.nlm.nih.gov/pubmed/25955980