API: Alba-Derm

What Is Alba-Derm and How Does It Work?

Alba-derm is a unique oil-in-water cream base made from a homogenous mixture of white petrolatum, mineral oil, chlorocresol, cetomacrogol 1000, cetostearyl alcohol, and water. The cream is both paraben-free and stable over pHs ranging from 2 to 12, making it a superior choice for use in topical pharmaceutical medications. Alba-Derm can be used to deliver salts and lipophilic and hydrophilic drugs transdermally. The emollient is also suitable for use as a cosmetic moisturizer or ointment, perhaps for delivering topical herbal supplements and other natural remedies for rashes, dry skin, and insect bites.

For more information, including a MSDS sheet, please see PNA’s Alba-Derm page.

Ingredients of Alba-Derm

  • White Petrolatum: White petrolatum is a semi-solid mixture of hydrocarbons derived from petroleum. The substance works as an emollient that forms an oily layer on top of skin in order to protect the skin from drying out.
  • Mineral Oil: Mineral oil is a clear, odorless product also derived from petroleum. Because the mineral oil stays semisolid, it cannot clog skin pores. The substance rarely causes allergies and is often used with white petrolatum.
  • Chlorocresol: Chlorocresol has both disinfectant and antiseptic properties, and is often used to prepare and disinfect skin wounds. The substance may also be used as a preservative in creams that contain water.1
  • Cetomacrogol 1000: Cetomacrogol 1000 is an oil-in-water emulsifier that can solubilize essential oils, vitamin oils, and drugs that have poor solubility in water. The substance is stable in strong acids to alkaline pHs.2
  • Cetostearyl Alcohol: Cetostearyl alcohol is a mixture of cetyl and stearyl alcohols and is classified as a fatty alcohol. The substance is soluble in oil but not in water and is used as an emulsion stabilizer, opacifying agent, surfactant, and to increase viscosity of the cream.3
  • Water: Oil-in-water formulations make the cream non-greasy and easy to wash off.

Side Effects

Alba-Derm is generally safe to use in topical preparations, but may cause irritation in the eyes, skin, or respiratory tract. If ingested or inhaled, the cream should be washed away with water and patient should breathe in fresh air. Induced vomiting is not advised. If patient experiences skin irritation, water and soap should be used to wash the cream away.

Storage

Alba-Derm should be stored in tight containers. The product may decompose into toxic carbon monoxide and carbon dioxide fumes, and should be disposed of according to federal and local laws and regulations.

Buying Guide

PNA is a recommended bulk supplier of Alba-Derm and other APIs. You can learn more about Alba-Derm here.

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Resources

Show 3 footnotes

  1. ” Chlorocresol,” 2014, http://druginfosys.com/Drug.aspx?drugCode=1309&drugName=&type=9
  2. “Product details: Cetomacrogol 1000,” 2016, http://www.crodahealthcare.com/home.aspx?print=1&view=dtl&d=content&s=149&r=346&p=2204&prodID=27&sumID=34&productname=&chemicaldescription=&chemicalgroup=&function=&application=
  3. “Cetostearyl Alcohol,” January 4, 2016, http://www.drugs.com/inactive/cetostearyl-alcohol-17.html